LABORATORY LINE

CONTINUOUS FLOW SYNTHESIS IN
MICROSTRUCTURED REACTORS — A NEW WAY
OF THINKING CHEMICAL SYNTHESIS
 

In recent years, Flow Reaction Technology has evolved as a beneficial, innovative tool for the improvement and optimization of reactions. Based on its unique miniaturization approach, Flow Reaction Technology allows you to carry out reactions under flow-through conditions.

Organic chemists usually spend a substantial amount of time on the development of synthetic routes to new materials. The best pathways need to be chosen and reaction conditions must be optimized. Once a product is successful and demand for larger quantities is growing, the whole synthesis process needs to be revised again and readjusted for larger batch sizes.

 

This general procedure shows a typical problem in conventional batch synthesis: batch synthesis is a space-resolved process. The output of the reaction is determined by the size of the reaction vessel – the larger the vessel the higher the output of the reaction.

 

In sharp contrast to the batch mode, chemical synthesis becomes a time-resolved process in flow chemistry. Reagent streams are continuously pumped into a flow reactor where they are mixed and allowed to react. The product instantly leaves the reactor as a continuous stream. Therefore, only flow rate and operation time determine the synthesis scale. Identical reactors with an inner volume of less than a milliliter will produce kilogram quantities of material when operated for a whole day at fast flow rates, or small milligram batches if operated for a few minutes.

OUR STANDARD COMPONENTS FOR FLOW CHEMISTRY

High Precision Pumps neMESYS

 

neMESYS Base Module                                            

Low Pressure Pump Module neMESYS               

Mid Pressure Pump Module neMESYS                 

High Pressure Pump Module neMESYS               

Ultra High Pressure Pump Module neMESYS

 

Microreactor System Qmix

 

Qmix Base Module

Heating Module Qmix Q+

Heating Module Qmix Q+

Cooling Module Qmix Q

Pressure Measurement Module Qmix p 

Black Pressure Regulation Module Qmix BPR

Spectrometer Module Qmix l VIS

Spectrometer Module Qmix l UV/VIS

Spectrometer Module Qmix l NIR

Sample Storage Module Qmix rotAXYS

Input/Output Module Qmix I/O

 

Stainless Steel Syringes

 

Mid Pressure Stainless Steel Syringe 2,5 ml               

Mid Pressure Stainless Steel Syringe 10 ml                   Mid Pressure Stainless Steel Syringe 25 ml                

Mid Pressure Stainless Steel Syringe 50 ml                  

High Pressure Stainless Steel Syringe 2.5 ml               

High Pressure Stainless Steel Syringe 10 ml                

High Pressure Stainless Steel Syringe 20 ml                

High Pressure Stainless Steel Syringe 50 ml                

High Pressure Stainless Steel Syringe 100 ml              

Ultra High Pressure Stainless Steel Syringe 10 ml      

Ultra High Pressure Stainless Steel Syringe 25 ml      

Ultra High Pressure Stainless Steel Syringe 100 ml    

Ultra High Pressure Stainless Steel Syringe 250 ml

 

Glas Syringes

 

Glas Syringe 1 ml

Glas Syringe 2,5 ml

Glas Syringe 5 ml 

Glas Syringe 10 ml

Glas Syringe 25 ml

Glas Syringe 50 ml

 

Check Valve cetoni 

A3921000059      

A3921000080      

A3921000081       

A3921000084       

A3921000082

 

 

 

A2033000018

A2033000019

A2033000010

A2033000015

A2033000011

A2033000016

A2033000012

A2033000020

 

A2030000013

A2033000014

 

 

A2019000032

A2019000031        

A2019000030        

A2019000029        

A2019000072

A2019000074 

A2019000076        

A2019000078        

A2019000080        

A2019000060        

A2019000104        

A2019000106        

A2019000108

 

 

M1101000040

M1101000048

M1101000051

M1101000041

M1101000060

M1101000059

 

A2019000059

for neMESYS pump modules, 120 W

with check valves, max. pressure 3 bar

with check valves, max. pressure 195 bar

with check valves and p-sensor, max. pressure 510 bar

with check valves and p-sensor, max. pressure 890 bar

 

 

 

for Qmix system, 600 W

stainless steel mixer & brass reactor, T +25 – +250 °C

glas mixer & teflon reactor, T +25 – +250 °C

Peltie elements, T -80 – +100 °C

back pressure control

automatical back pressure regulator

VIS wave length 350 – 800 nm STS

UV/VIS wave length 200 – 850 nm

NIR wave length 650 – 1100 nm

sample storage module

automation module

 

 

mid pressure syringe, max. pressure 195 bar

mid pressure syringe, max. pressure 50 bar

mid pressure syringe, max. pressure 20 bar

mid pressure syringe, max. pressure 10 bar

high pressure syringe, max. pressure 510 bar

high pressure syringe, max. pressure 120 bar

high pressure syringe, max. pressure 50 bar

high pressure syringe, max. pressure 25 bar

high pressure syringe, max. pressure 12 bar

ultra high pressure syringe, max. pressure 890 bar

ultra high pressure syringe, max. pressure 345 bar

ultra high pressure syringe, max. pressure 85 bar

ultra high pressure syringe, max. pressure 35 bar

 

 

las syringe, max. pressure 37 bar

glas syringe, max. pressure 23 bar

glas syringe, max. pressure 17 bar

glas syringe, max. pressure 13 bar

glas syringe, max. pressure 11 bar

glas syringe, max. pressure 8,1 bar

 

check valve for neMESYS pump modules

Even constructive changes of single components are possible on request.